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Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to  foresee the complexities of personalized medicine | Journal of Molecular  Signaling | Full Text
Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine | Journal of Molecular Signaling | Full Text

ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin–DNA adducts -  ScienceDirect
ABT-737 overcomes Bcl-2 mediated resistance to doxorubicin–DNA adducts - ScienceDirect

Chemical structure and mode of action of the BH3 mimetic ABT-737 in... |  Download Scientific Diagram
Chemical structure and mode of action of the BH3 mimetic ABT-737 in... | Download Scientific Diagram

Targeting Multiple Arms of the Apoptotic Regulatory Machinery | Cancer  Research
Targeting Multiple Arms of the Apoptotic Regulatory Machinery | Cancer Research

Attacking cancer's Achilles heel: antagonism of anti‐apoptotic BCL‐2 family  members - Opferman - 2016 - The FEBS Journal - Wiley Online Library
Attacking cancer's Achilles heel: antagonism of anti‐apoptotic BCL‐2 family members - Opferman - 2016 - The FEBS Journal - Wiley Online Library

Synergistic co-delivery of diacid metabolite of norcantharidin and ABT-737  based on folate-modified lipid bilayer-coated mesoporous silica  nanoparticle against hepatic carcinoma | SpringerLink
Synergistic co-delivery of diacid metabolite of norcantharidin and ABT-737 based on folate-modified lipid bilayer-coated mesoporous silica nanoparticle against hepatic carcinoma | SpringerLink

PROTACs are effective in addressing the platelet toxicity associated with  BCL-XL inhibitors
PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors

The regulation of MCL-1 by Noxa expression and the mechanisms of... |  Download Scientific Diagram
The regulation of MCL-1 by Noxa expression and the mechanisms of... | Download Scientific Diagram

Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions  with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2,  Bcl-xL, and Mcl-1 | Molecular and Cellular Biology
Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2, Bcl-xL, and Mcl-1 | Molecular and Cellular Biology

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT- 737 in acute myeloid leukemia - ScienceDirect
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT- 737 in acute myeloid leukemia - ScienceDirect

The Stress Protein BAG3 Stabilizes Mcl-1 Protein and Promotes Survival of  Cancer Cells and Resistance to Antagonist ABT-737* - Journal of Biological  Chemistry
The Stress Protein BAG3 Stabilizes Mcl-1 Protein and Promotes Survival of Cancer Cells and Resistance to Antagonist ABT-737* - Journal of Biological Chemistry

Cancers | Free Full-Text | The Application of Arsenic Trioxide in  Ameliorating ABT-737 Target Therapy on Uterine Cervical Cancer Cells  through Unique Pathways in Cell Death | HTML
Cancers | Free Full-Text | The Application of Arsenic Trioxide in Ameliorating ABT-737 Target Therapy on Uterine Cervical Cancer Cells through Unique Pathways in Cell Death | HTML

ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases  antimitotic-mediated apoptosis in human prostate cancer cells [PeerJ]
ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells [PeerJ]

Targeting BCL-2 in B-cell malignancies and overcoming therapeutic  resistance | Cell Death & Disease
Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance | Cell Death & Disease

ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of  apoptosis in multiple myeloma cells | Leukemia
ABT-737, an inhibitor of Bcl-2 family proteins, is a potent inducer of apoptosis in multiple myeloma cells | Leukemia

Inner Mitochondrial Membrane Disruption Links Apoptotic and  Agonist-Initiated Phosphatidylserine Externalization in Platelets |  Arteriosclerosis, Thrombosis, and Vascular Biology
Inner Mitochondrial Membrane Disruption Links Apoptotic and Agonist-Initiated Phosphatidylserine Externalization in Platelets | Arteriosclerosis, Thrombosis, and Vascular Biology

B Cell Lymphoma 2 and Cancer Therapy | Encyclopedia MDPI
B Cell Lymphoma 2 and Cancer Therapy | Encyclopedia MDPI

Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby  increasing drug resistance | EMBO reports
Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance | EMBO reports

Discovery of Marinopyrrole A (Maritoclax) as a Selective Mcl-1 Antagonist  that Overcomes ABT-737 Resistance by Binding to and Targeting Mcl-1 for  Proteasomal Degradation* - Journal of Biological Chemistry
Discovery of Marinopyrrole A (Maritoclax) as a Selective Mcl-1 Antagonist that Overcomes ABT-737 Resistance by Binding to and Targeting Mcl-1 for Proteasomal Degradation* - Journal of Biological Chemistry

Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to  foresee the complexities of personalized medicine | Journal of Molecular  Signaling | Full Text
Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine | Journal of Molecular Signaling | Full Text

In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive  Myc-driven lymphomas | PNAS
In vivo efficacy of the Bcl-2 antagonist ABT-737 against aggressive Myc-driven lymphomas | PNAS