Home

Heilige Hintergrund Hinweis ag490 mechanism of action Haufen Fähigkeit Reinheit

Antioxidants | Free Full-Text | Jak2 Inhibitor AG490 Improved Poststroke  Central and Peripheral Inflammation and Metabolic Abnormalities in a Rat  Model of Ischemic Stroke | HTML
Antioxidants | Free Full-Text | Jak2 Inhibitor AG490 Improved Poststroke Central and Peripheral Inflammation and Metabolic Abnormalities in a Rat Model of Ischemic Stroke | HTML

GRAMD1B regulates cell migration in breast cancer cells through JAK/STAT  and Akt signaling | Scientific Reports
GRAMD1B regulates cell migration in breast cancer cells through JAK/STAT and Akt signaling | Scientific Reports

Nuclear Jak2 and Transcription Factor NF1-C2: a Novel Mechanism of  Prolactin Signaling in Mammary Epithelial Cells | Molecular and Cellular  Biology
Nuclear Jak2 and Transcription Factor NF1-C2: a Novel Mechanism of Prolactin Signaling in Mammary Epithelial Cells | Molecular and Cellular Biology

Effects of AG490 and EVO on PGI, the JAK2/STAT3 signaling pathway, and... |  Download Scientific Diagram
Effects of AG490 and EVO on PGI, the JAK2/STAT3 signaling pathway, and... | Download Scientific Diagram

An essential role of the JAK-STAT pathway in ischemic preconditioning | PNAS
An essential role of the JAK-STAT pathway in ischemic preconditioning | PNAS

Suppressor of Cytokine Signalling-6 Promotes Neurite Outgrowth via  JAK2/STAT5-Mediated Signalling Pathway, Involving Negative Feedback  Inhibition
Suppressor of Cytokine Signalling-6 Promotes Neurite Outgrowth via JAK2/STAT5-Mediated Signalling Pathway, Involving Negative Feedback Inhibition

Resveratrol provides neuroprotection by regulating the  JAK2/STAT3/PI3K/AKT/mTOR pathway after stroke in rats - ScienceDirect
Resveratrol provides neuroprotection by regulating the JAK2/STAT3/PI3K/AKT/mTOR pathway after stroke in rats - ScienceDirect

Antioxidants | Free Full-Text | Jak2 Inhibitor AG490 Improved Poststroke  Central and Peripheral Inflammation and Metabolic Abnormalities in a Rat  Model of Ischemic Stroke | HTML
Antioxidants | Free Full-Text | Jak2 Inhibitor AG490 Improved Poststroke Central and Peripheral Inflammation and Metabolic Abnormalities in a Rat Model of Ischemic Stroke | HTML

Effects of AG-490 on gp130-dependent signaling pathway in cardiac... |  Download Scientific Diagram
Effects of AG-490 on gp130-dependent signaling pathway in cardiac... | Download Scientific Diagram

Combination of AG490, a Jak2 inhibitor, and methylsulfonylmethane  synergistically suppresses bladder tumor growth via the Jak2/STAT3 pathway
Combination of AG490, a Jak2 inhibitor, and methylsulfonylmethane synergistically suppresses bladder tumor growth via the Jak2/STAT3 pathway

AG490 prevents cell death after exposure of rat astrocytes to hydrogen  peroxide or proinflammatory cytokines: involvement of the Jak2/STAT pathway  - Gorina - 2005 - Journal of Neurochemistry - Wiley Online Library
AG490 prevents cell death after exposure of rat astrocytes to hydrogen peroxide or proinflammatory cytokines: involvement of the Jak2/STAT pathway - Gorina - 2005 - Journal of Neurochemistry - Wiley Online Library

Combination of AG490, a Jak2 inhibitor, and methylsulfonylmethane  synergistically suppresses bladder tumor growth via the Jak2/STAT3 pathway
Combination of AG490, a Jak2 inhibitor, and methylsulfonylmethane synergistically suppresses bladder tumor growth via the Jak2/STAT3 pathway

AG490 suppresses EPO-mediated activation of JAK2-STAT but enhances blood  flow recovery in rats with critical limb ischemia | Journal of Inflammation  | Full Text
AG490 suppresses EPO-mediated activation of JAK2-STAT but enhances blood flow recovery in rats with critical limb ischemia | Journal of Inflammation | Full Text

Frontiers | Impact of Janus Kinase Inhibition on the Treatment of Axial  Spondyloarthropathies | Immunology
Frontiers | Impact of Janus Kinase Inhibition on the Treatment of Axial Spondyloarthropathies | Immunology

AG490 prevents cell death after exposure of rat astrocytes to hydrogen  peroxide or proinflammatory cytokines: involvement of the Jak2/STAT pathway  - Gorina - 2005 - Journal of Neurochemistry - Wiley Online Library
AG490 prevents cell death after exposure of rat astrocytes to hydrogen peroxide or proinflammatory cytokines: involvement of the Jak2/STAT pathway - Gorina - 2005 - Journal of Neurochemistry - Wiley Online Library

Effects of GA-A combined with AG490 on JAK2/STAT3 signaling. (A) The... |  Download Scientific Diagram
Effects of GA-A combined with AG490 on JAK2/STAT3 signaling. (A) The... | Download Scientific Diagram

Combination of AG490, a Jak2 inhibitor, and methylsulfonylmethane  synergistically suppresses bladder tumor growth via the Jak2/STAT3 pathway
Combination of AG490, a Jak2 inhibitor, and methylsulfonylmethane synergistically suppresses bladder tumor growth via the Jak2/STAT3 pathway

The Jak/STAT pathway is involved in synaptic plasticity. - Abstract -  Europe PMC
The Jak/STAT pathway is involved in synaptic plasticity. - Abstract - Europe PMC

Antioxidants | Free Full-Text | Jak2 Inhibitor AG490 Improved Poststroke  Central and Peripheral Inflammation and Metabolic Abnormalities in a Rat  Model of Ischemic Stroke | HTML
Antioxidants | Free Full-Text | Jak2 Inhibitor AG490 Improved Poststroke Central and Peripheral Inflammation and Metabolic Abnormalities in a Rat Model of Ischemic Stroke | HTML

AG490 inhibited IL-6-induced STAT3 activation. (A) AG490 (50 μM)... |  Download Scientific Diagram
AG490 inhibited IL-6-induced STAT3 activation. (A) AG490 (50 μM)... | Download Scientific Diagram

Dehydrocrenatidine Is a Novel Janus Kinase Inhibitor | Molecular  Pharmacology
Dehydrocrenatidine Is a Novel Janus Kinase Inhibitor | Molecular Pharmacology

Mechanism of activation of JAK/STAT signaling by IFN- ␥ in primary... |  Download Scientific Diagram
Mechanism of activation of JAK/STAT signaling by IFN- ␥ in primary... | Download Scientific Diagram

AG490 prevents cell death after exposure of rat astrocytes to hydrogen  peroxide or proinflammatory cytokines: involvement of the Jak2/STAT pathway  - Gorina - 2005 - Journal of Neurochemistry - Wiley Online Library
AG490 prevents cell death after exposure of rat astrocytes to hydrogen peroxide or proinflammatory cytokines: involvement of the Jak2/STAT pathway - Gorina - 2005 - Journal of Neurochemistry - Wiley Online Library

Inhibition of phosphotyrosine STAT3 by AG490 triggers down-regulation... |  Download Scientific Diagram
Inhibition of phosphotyrosine STAT3 by AG490 triggers down-regulation... | Download Scientific Diagram

AG490 and MSM combination exposure leads to the downregulation of STAT3...  | Download Scientific Diagram
AG490 and MSM combination exposure leads to the downregulation of STAT3... | Download Scientific Diagram

AG490 prevents cell death after exposure of rat astrocytes to hydrogen  peroxide or proinflammatory cytokines: involvement of the Jak2/STAT pathway  - Gorina - 2005 - Journal of Neurochemistry - Wiley Online Library
AG490 prevents cell death after exposure of rat astrocytes to hydrogen peroxide or proinflammatory cytokines: involvement of the Jak2/STAT pathway - Gorina - 2005 - Journal of Neurochemistry - Wiley Online Library

Inhibition of JAK2/STAT3 signaling suppresses bone marrow stromal cells  proliferation and osteogenic differentiation, and impairs bone defect  healing
Inhibition of JAK2/STAT3 signaling suppresses bone marrow stromal cells proliferation and osteogenic differentiation, and impairs bone defect healing

Constitutively Active Gα16 Stimulates STAT3 via a c-Src/JAK- and  ERK-dependent Mechanism* - Journal of Biological Chemistry
Constitutively Active Gα16 Stimulates STAT3 via a c-Src/JAK- and ERK-dependent Mechanism* - Journal of Biological Chemistry