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Chemical modifications of G418 (geneticin): Synthesis of novel readthrough aminoglycosides results in an improved in vitro safety window but no improvements in vivo - ScienceDirect
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Repairing faulty genes by aminoglycosides: Development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations - ScienceDirect
![Comparison of read-through effects of aminoglycosides and PTC124 on rescuing nonsense mutations of HERG gene associated with long QT syndrome Comparison of read-through effects of aminoglycosides and PTC124 on rescuing nonsense mutations of HERG gene associated with long QT syndrome](https://www.spandidos-publications.com/article_images/ijmm/33/3/IJMM-33-03-0729-g04.jpg)
Comparison of read-through effects of aminoglycosides and PTC124 on rescuing nonsense mutations of HERG gene associated with long QT syndrome
![Structure of G418 and gentamicin complex components. The structure on... | Download Scientific Diagram Structure of G418 and gentamicin complex components. The structure on... | Download Scientific Diagram](https://www.researchgate.net/publication/328523837/figure/fig2/AS:685818247139328@1540523220050/Structure-of-G418-and-gentamicin-complex-components-The-structure-on-the-top-left-and.png)
Structure of G418 and gentamicin complex components. The structure on... | Download Scientific Diagram
![Designer Aminoglycosides That Selectively Inhibit Cytoplasmic Rather than Mitochondrial Ribosomes Show Decreased Ototoxicity - Journal of Biological Chemistry Designer Aminoglycosides That Selectively Inhibit Cytoplasmic Rather than Mitochondrial Ribosomes Show Decreased Ototoxicity - Journal of Biological Chemistry](https://www.jbc.org/cms/asset/cf992362-6dfb-4510-a397-ff51350851c3/gr1.jpg)
Designer Aminoglycosides That Selectively Inhibit Cytoplasmic Rather than Mitochondrial Ribosomes Show Decreased Ototoxicity - Journal of Biological Chemistry
![Structures of the aminoglycoside geneticin (also named G418) [63, 64],... | Download Scientific Diagram Structures of the aminoglycoside geneticin (also named G418) [63, 64],... | Download Scientific Diagram](https://www.researchgate.net/publication/6381808/figure/fig3/AS:724636073472000@1549778111523/Structures-of-the-aminoglycoside-geneticin-also-named-G418-63-64-the-1-2.png)
Structures of the aminoglycoside geneticin (also named G418) [63, 64],... | Download Scientific Diagram
![A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion | Nature Communications A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion | Nature Communications](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41467-021-24575-x/MediaObjects/41467_2021_24575_Fig1_HTML.png)
A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion | Nature Communications
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Cancers | Free Full-Text | Inhibition of the Eukaryotic 80S Ribosome as a Potential Anticancer Therapy: A Structural Perspective
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